Second Generation 18F-labeled PSMA Targeted Imaging Agent Found to be Highly Sensitive in Detecting

[18F]DCFPyL is a 2nd generation small-molecule PET agent that attaches to the prostate-specific membrane antigen (PSMA). Signals from [18F]DCFPyL can then be measured via a PET scan. The study demonstrated that [18F]DCFPyL produced images that showed lower blood pool activity, providing clearer images than the 1st generation agent, [18F]DCFBC, produced by the same group. The study also showed 50 percent lower radiation dose in the most sensitive organs.

The World Molecular Imaging Society (WMIS) has provided unrestricted online access to the full text of this first-in-human study.

#PET #18F #PSMA